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Filtered Search Results
![eMolecules Pharmablock 3-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid 250mg 781214494 PBY0211 0 000 557756-85-1 MFCD06656472 487 549 C26H33NO8](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
eMolecules Pharmablock 3-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid 250mg 781214494 PBY0211 0 000 557756-85-1 MFCD06656472 487 549 C26H33NO8
Pharmablock 3-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid 250mg 781214494 PBY0211 0 000 557756-85-1 MFCD06656472 487 549 C26H33NO8
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eMolecules Advanced ChemBlocks (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-hydroxybutanoic acid 250mg 843717772 V143912 97 000 461692-98-8 MFCD06410792 341 363 C19H19NO5
Advanced ChemBlocks (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-hydroxybutanoic acid 250mg 843717772 V143912 97 000 461692-98-8 MFCD06410792 341 363 C19H19NO5
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Medchemexpress LLC Indomethacin (sodium hydrate) | 74252-25-8 | 99.9% | C19H21CINNaO7 | 1 G
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Indomethacin sodium hydrate is an orally active and BBB-permeable COX1/2 inhibitor, with IC50 values of 18 nM for COX-1 and 26 nM for COX-2. It exhibits anticancer and anti-infective activities and can be utilized in research related to cancer, inflammation, and viral infections.
- Orally active and BBB-permeable COX1/2 inhibitor
- Inhibits COX-1 with an IC50 of 18 nM
- Inhibits COX-2 with an IC50 of 26 nM
- Exhibits in vitro anticancer activity
- Protects host cells from viral damage
- Used in research for cancer, inflammation, and viral infections
- Can be used to create gastric ulcer models
- Rapidly absorbed after oral administration
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eMolecules 2098497-06-2 | ChemScene | tert-Butyl (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-aminopropanoate hydrochloride | 100mg | 687355707 | CS-0166834 | MFCD21363165 | 418.92 | C22H27ClN2O4
Pharmablock | ethyl 2-oxo-2-(thiophen-2-yl)acetate | 100mg | 784545717 | PB03700 | 4075-58-5 | MFCD00015538 | 184.210 | C8H8O3S
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eMolecules Pharmablock tert-butyl (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-iodo-propanoate 50mg 823750172 PBTFN18 0 000 282734-33-2 MFCD11053633 493 341 C22H24INO4
Pharmablock tert-butyl (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-iodo-propanoate 50mg 823750172 PBTFN18 0 000 282734-33-2 MFCD11053633 493 341 C22H24INO4
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eMolecules Pharmablock tert-butyl (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-iodo-propanoate 250mg 823750174 PBTFN18 0 000 282734-33-2 MFCD11053633 493 341 C22H24INO4
Pharmablock tert-butyl (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-iodo-propanoate 250mg 823750174 PBTFN18 0 000 282734-33-2 MFCD11053633 493 341 C22H24INO4
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eMolecules Pharmablock 3-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid 100mg 781214493 PBY0211 0 000 557756-85-1 MFCD06656472 487 549 C26H33NO8
Pharmablock 3-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid 100mg 781214493 PBY0211 0 000 557756-85-1 MFCD06656472 487 549 C26H33NO8
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eMolecules Pharmablock tert-butyl (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-iodo-propanoate 25mg 823750171 PBTFN18 0 000 282734-33-2 MFCD11053633 493 341 C22H24INO4
Pharmablock tert-butyl (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-iodo-propanoate 25mg 823750171 PBTFN18 0 000 282734-33-2 MFCD11053633 493 341 C22H24INO4
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Cayman Chemical IndomethacIn heptyl ester 50mg
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A potent, non-selective COX-2 inhibitor (IC50 = 0.04 µM); >1,700 times more potent as an inhibitor of COX-2 than COX-1
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Cayman Chemical IndomethacIn N-octyl amIde 1mg
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Indomethacin is a potent but non-selective inhibitor of both COX-1 and COX-2 in sheep and humans.{1286} Structurally, indomethacin is a substituted indole acetic acid, wherein the carboxylate can be derivitized as an ester or amide. These derivatives show enhanced selectivity for the COX-2 isoform. For example, the IC50 values of indomethacin N-octyl amide for the inhibition of ovine COX-1 and human recombinant COX-2 are 66 µM and 40 nM, respectively, making it 1,650 times more potent as an inhibitor of COX-2 than COX-1.{8243} While indomethacin itself has an IC50 of 0.05 µM for the inhibition of COX-2, it also inhibits COX-1 with a corresponding IC50 of 0.67 µM.
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eMolecules Pharmablock (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-fluorophenyl)propanoic acid 250mg 825885799 PBT4321 0 000 169243-86-1 MFCD00191197 405 425 C24H20FNO4
Pharmablock (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-fluorophenyl)propanoic acid 250mg 825885799 PBT4321 0 000 169243-86-1 MFCD00191197 405 425 C24H20FNO4
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eMolecules Pharmablock (2S)-3-cyclobutyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid 25mg 788493646 PBA0248 0 000 478183-62-9 MFCD03840400 365 429 C22H23NO4
Pharmablock (2S)-3-cyclobutyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid 25mg 788493646 PBA0248 0 000 478183-62-9 MFCD03840400 365 429 C22H23NO4
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Sigma Aldrich Fine Chemicals Biosciences Indomethacin 98.5 100.5 in100G
Indomethacin is an inhibitor of the enzyme cyclooxygenase 1 and 2. Indomethacin elicits side effects in gastrointestinal tract kidney and cerebrum. Indomethacin along with ibuprofen is effective for treating patent ductus arteriosus (PDA) in infants with respiratory distress syndrome. Rectal indomethacin is effective in treating endoscopic retrograde cholangiography (ERCP) induced pancreatitis.
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eMolecules Pharmablock (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methoxy-butanoic acid 100mg 812212341 PBA0050 0 000 1272755-48-2 MFCD07366856 355 390 C20H21NO5
Pharmablock (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methoxy-butanoic acid 100mg 812212341 PBA0050 0 000 1272755-48-2 MFCD07366856 355 390 C20H21NO5
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eMolecules Pharmablock (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propanoic acid 500mg 788592968 PBYL049 0 000 86123-10-6 MFCD00062955 387 435 C24H21NO4
Pharmablock (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propanoic acid 500mg 788592968 PBYL049 0 000 86123-10-6 MFCD00062955 387 435 C24H21NO4
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